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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Stoffel Brandy

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#protein folding Open access Oct 2026

Spindle Pole Coupling Failure as a Progressive Driver of Differentiation Suppression in Cancer Initiation

Background: Current cancer initiation models, including multi-hit genomic models and chromosomal instability (CIN) frameworks, do not account for a mechanistically distinct upstream event: progressive protein coupling failure at the spindle pole during mitosis. We propose a novel hypothesis in which coupling failure am...

Stoffel Brandy · 0 citations

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