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Author

Sudarshan Gadadhar

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Aug 2026

Conformational activation of GSK3β by an environmental toxicant suppresses hedgehog signalling and disrupts ciliary homeostasis

It is shown that endosulfan, a banned organochlorine pesticide linked to congenital and reproductive defects, suppresses hedgehog signalling by driving proteolytic processing of GLI transcription factors into repressor forms, establishing a chemical–biological axis through which an environmental toxicant hijacks core k...

Ravikant Piyush, Himani Barmola, A. Bhattacharjya et al. · 0 citations

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