In silico evaluation of deleterious nsSNPs in SOD1 and TARDBP genes associated with amyotrophic lateral sclerosis
Network and pathway analyses highlighted SOD1 and TARDBP as key nodes in ALS-related mechanisms, such as oxidative stress, RNA metabolism, proteostasis, and mitochondrial impairment, and network-based functions were combined.
Manjunath B. Malshetty, Sandeep Mallya, Sudharshan Prabhu
· Scientific Reports · 0 citations