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Author

Sulagna Sanyal

2 papers indexed here

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Jul 2026

YY1 regulates B cell lineage plasticity via transcriptional, miRNA post-transcriptional, and epigenetic mechanisms 2299696

YY1 is essential for embryogenesis, cell proliferation, and lineage differentiation. It regulates genes via co-activators, co-repressors, or PcG complexes. In hematopoiesis, YY1 controls stem cell differentiation, and its loss at the pro-B stage halts B-cell development. Bulk RNA-seq of WT and YY1-KO pro-B...

Nasreen Bano, Sarah Naiyer, Sulagna Sanyal et al. · 0 citations
Open access Sep 2026

miRNA-mediated regulation of lineage plasticity in YY1 knockout pro-B cells

It is suggested that YY1 preserves B cell identity through coordinated regulation of transcriptional and post-transcriptional programs, with YY1-dependent miRNA networks contributing to the maintenance of B cell-associated gene expression and restriction of alternative lineage programs.

Nasreen Bano, Sarah Naiyer, Sulagna Sanyal et al. · 0 citations

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