Regulation of a Classical Allosteric Molecular Machine by an Intrinsically Disordered Domain: the C-termini of GroEL
A regulatory role is identified for the conserved, intrinsically disordered C-terminal tails of GroEL, one of the best-studied ATP-dependent chaperones, to reveal how the conformational properties of an intrinsically disordered element can be exploited to optimize the energetic efficiency and functional timing of a lar...
Morgan Powers, Kacie A. Evans, Sun He et al.
· bioRxiv · 0 citations