Author

Sungbo Hwang

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#protein folding Oct 2026

Label-Free YaxAB Nanopore Fingerprinting of Cancer-Associated Single-Residue Bcl-xL Variants.

Resolving cancer-associated protein variants remains difficult when variants share similar molecular masses and folded structures. Conventional assays often require labels or provide ensemble-averaged readouts, limiting their ability to resolve subtle variant differences. Here, a YaxAB nanopore workflow is presented fo...

Min-Ji Chung, Sohee Oh, Jin-Sik Kim et al. · Small Methods · 0 citations

#protein folding Open access Sep 2026

ProtThermoRank: Sequence-based multi-class prediction model for protein thermal stability changes and its application to CcsZ.

Results demonstrated that ProtThermoRank provides a sequence-based approach for artificial intelligence-guided protein engineering, enabling in-silico high-throughput screening of thermostabilizing variants and accelerating the discovery and optimization of highly stabilizing proteins.

Sungbo Hwang, Sohee Oh, Jin-Sik Kim et al. · International Journal of Bio... · 0 citations