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Open access Aug 2026

Tunable AMPA receptor function via recurrent evolution of heterotetramers

AMPA receptors are glutamate receptors specific to bilaterian animals with complex nervous systems. Wang et al. investigated the biophysical function, pharmacology, and kinetics of AMPA receptors from diverse bilaterians, uncovering convergent evolution on functional hallmarks, such as heteromerization and channel prop...

Yu-Hong Wang, Alexander Edwards, Jelena Baranovic et al. · 0 citations

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