Summary Paragraph Personality traits describe stable differences in how people think, feel, and behave and how they interact with and experience their social and physical environments1,2. Many questions remain unanswered about associations between DNA and personality traits, such as their robustness, generalizability,...
T. Schwaba, Margaret L. Clapp Sullivan, W. Akingbuwa et al.· Nature· 5 citations· ⚡1
Social behaviour is a heritable trait linked to well-being and mental health, yet it varies across social context, including social domains, informants and development, which may shape its underlying genomic architecture. Here, we conducted a genome-wide meta-regression meta-analysis of social behaviour from infancy to...
L. de Hoyos, Fenja Schlag, Sanjeevan Jahagirdar et al.· Nature Human Behaviour· 0 citations
OBJECTIVES
Healthcare costs are a major and growing burden in many societies and primarily driven by non-communicable diseases, which are strongly linked to physical fitness. In this study, we explored whether physical fitness is associated with healthcare costs, and whether this association is causal.
METHODS
We use...
M. Vaaramo, J. Kari, Raija Korpelainen et al.· Medicine & Science in Sports...· 0 citations
A meta-GWAS with seven studies of European ancestry identified for the first time a robust chromosomal region associated with emotional eating in seven studies, supporting the hypothesis that shared genetic factors may influence both eating behavior traits and obesity risk.
M. Muntaner, K. Horn, B. de Lauzon-Guillain et al.· Molecular Psychiatry· 0 citations
The potential of plasma proteomic clocks in detecting AD‐related phenotypes and co‐morbidities possibly constitute confounding factors, compromising the performance of proteomic aging models is illustrated.
Cindy David Sarmento, G. Drouard, T. Saari et al.· Alzheimer's & Dementia· 1 citation
A genomic meta-analysis of case–control studies of binge-eating behavior and analyses of anorexia nervosa and its subtypes, alongside analyses of AN, identified six BE-associated loci and eight areas that are associated with anorexia nervosa, in people of European ancestry.
Jet D. Termorshuizen, Helena L. Davies, Sang-Hyuck Lee et al.· Nature Mental Health· 1 citation
BPD showed the strongest positive genetic correlations with GWAS of post-traumatic stress disorder, depression, attention deficit hyperactivity disorder, antisocial behavior, antisocial behavior, and measures of suicide and self-harm.
F. Streit, S. Awasthi, Alisha S. M. Hall et al.· Nature Genetics· 1 citation
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