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T. Waterboer

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Open access Aug 2026

Lytic Epstein-Barr virus infection and emerging autoantibodies precede multiple sclerosis prodrome.

Epstein-Barr virus (EBV) is a critical risk factor for multiple sclerosis (MS), but the pathogenic mechanisms remain elusive. To clarify its role in MS, we examined the sequence of EBV-related antibody responses over a broad period before the clinical onset of MS, from early childhood to middle age. A nested case-contr...

Viktor Grut, Jens Ingvarsson, Martin Biström et al. · 0 citations
Review Open access Aug 2026

No clear evidence for relationships of apolipoprotein E genotype with measures of common infections in three UK cohorts

APOE genotype is a very strong genetic risk factor for late-onset Alzheimer’s disease (AD). This relationship may involve mediation by common infections—several of which are also dementia risk factors. We investigated associations of APOE ε2 and ε4 carriage with serostatus and antibody titres to 14 common pathog...

R. Green, A. Fernández-Sanlés, Caterina Felici et al. · 0 citations
Review Jul 2026

A scalable high-throughput serolomics platform for profiling serum antibody responses in large-scale population-based cohorts.

An automated assay platform that robustly quantifies antibodies against up to 100 antigens in a single reaction, using Luminex suspension array technology, alongside generating ample quality control measures is described.

Lea Kröller, Rima Jeske, Birgitta E. Michels et al. · 1 citation

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