Epstein-Barr virus (EBV) is a critical risk factor for multiple sclerosis (MS), but the pathogenic mechanisms remain elusive. To clarify its role in MS, we examined the sequence of EBV-related antibody responses over a broad period before the clinical onset of MS, from early childhood to middle age. A nested case-contr...
Viktor Grut, Jens Ingvarsson, Martin Biström et al.· Brain : a journal of neurolo...· 0 citations
APOE
genotype is a very strong genetic risk factor for late-onset Alzheimer’s disease (AD). This relationship may involve mediation by common infections—several of which are also dementia risk factors. We investigated associations of
APOE
ε2 and ε4 carriage with serostatus and antibody titres to 14 common pathog...
R. Green, A. Fernández-Sanlés, Caterina Felici et al.· Scientific Reports· 0 citations
An automated assay platform that robustly quantifies antibodies against up to 100 antigens in a single reaction, using Luminex suspension array technology, alongside generating ample quality control measures is described.
Lea Kröller, Rima Jeske, Birgitta E. Michels et al.· Nature Protocols· 1 citation
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