Open access
Jul 2025
Design and model choices shape inference of age-varying genetic effects on complex traits
Understanding how genetic influences on complex traits change with age is a fundamental question in genetic epidemiology. Both cross-sectional (between-subject) and longitudinal (within-subject) approaches can contribute to answering this question but come with distinct strengths and limitations. Here we show that age-...
T. Schoeler, S. Wiegrebe, T. Winkler et al.
· Nature Aging · 2 citations