Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Adoptive transfer of proinflammatory myeloid cells enhances antitumor T‐cell responses and limits tumor growth in murine models. Previous work identified transcription factors NF‐κB p50 and STAT6 as key regulators whose inactivation enhances the inflammatory potential of murine myeloid cells. Herein, we translate murin...
Theresa Barberi, Alan D. Friedman
· Molecular Oncology · 0 citations