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Author

Thierry Forné

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2 papers indexed here

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Open access Sep 2026

Genomic imprinting of the metabolic regulator gene Klf14 is regulated by a paternal sub-TAD anchored at Mest.

KLF14 acts as a master regulator of gene expression in adipose tissue and variants at the human KLF14 gene show reproducible association with type 2 diabetes and metabolic syndrome. Risk alleles are only pathological when maternally inherited, consistent with the observation that KLF14/Klf14 is a maternally expressed i...

Amanda Ha, Natsuki Hayashi, Aaron B. Bogutz et al. · 0 citations
Open access Jul 2026

Lineage-specific regulation and RNA-associated functions of SATB1 in mature B-cells

It is shown that Satb1 expression in mature B cells is controlled by alternative promoter usage and splicing, with promoters P1 and P3 dynamically switching upon LPS-induced activation, while P2 remains transcriptionally silent.

Jean-Yves Alejandro Frayssinhes, Lya Meriot, Tiffany Marchiol et al. · 0 citations

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