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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Tian-Chen Li

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#protein folding Sep 2026

A conformational switch governs the dual role of liquid–liquid phase separation in amyloid fibrillization

Biomolecular condensates provide dynamic environments that store and organize proteins, yet the fundamental principles determining whether condensation promotes or suppresses irreversible protein aggregation remain unclear. Here, we show that the receptor-interacting protein kinase 3 (RIPK3) RHIM domain follows distinc...

Tian-Chen Li, Brayden C. Williams, Qi Han et al. · 0 citations
Review Open access Sep 2026

Probing biomolecular condensates with a minimally perturbative experimental readout framework

Abstract Biomolecular condensates are membrane-less compartments formed through phase separation that concentrate and organize biomolecules within cells. Far from being static droplets, they are dynamic molecular assemblies whose internal dynamics, structure, mechanics, and composition can evolve over time during cellu...

Jia-Xing Xie, Benedict Tai, Tian-Chen Li et al. · 0 citations

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