Tian-Yu Lu

Trion-1: Unifying Language, Protein Sequence, and Structure with Diffusion Language Models

This work introduces Trion-1, the first native, unified, multimodal diffusion language model (dLLM) for proteins, which unifies six core capabilities: folding, inverse folding, sequence understanding, structure understanding, sequence design, and structure design, while retaining the native language capabilities of gen...