Mechanisms of Lipid Metabolism Disorders in Experimental Non-Alcoholic Fatty Liver Disease: The Role of LDLR, LOX-1, ApoE and LRP1
Background: Non-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disorder and is closely linked to insulin resistance and the metabolic syndrome. Beyond the accumulation of triacylglycerides (TAG), disturbed hepatic cholesterol handling — mediated by the low-density lipoprotein receptor...