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V. Bypaneni

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Sep 2026

Forced Degradation Profiling and Putative Structural Characterization of Atogepant Degradation Products by LC‐QTOF‐MS/MS Supported by In‐Silico Degradation‐Pathway and Toxicity Assessments

Atogepant is an approved medicine prescribed to be administered by oral route to help prevent migraine headaches in adults. The present study aimed to develop a stability‐indicating RP‐HPLC method for quantifying atogepant and its degradation products (DPs) in atogepant active ingredient. The structure assessment of...

Jayaram Kamma, Murugesan Palanivelu, V. Bypaneni et al. · 0 citations
Open access Aug 2026

A Green Analytical Stability Indicating RP HPLC Method for Determination of Related Impurities in Istradefylline Dosage Forms. Robustness Study by Quality by Design Approach

A novel, stability-indicating, Quality by Design (QbD)-based and eco-friendly RP-HPLC method was developed and validated for the determination of Istradefylline and its related impurities in tablet dosage forms, demonstrating excellent specificity.

V. Bypaneni, Padmakar Gandla, Murugesan Palanivelu et al. · 0 citations

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