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V. Palande

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Open access Aug 2026

Factors impacting protective immunity conferred by vaccination with adeno-associated virus-like particles displaying human papillomavirus L2 residues 17–36

ABSTRACT A phase I study was conducted in 20 healthy subjects with 20 µg adeno-associated virus 2 (AAV2)-like particles displaying L2 residues 17–36 of both human papillomavirus (HPV) type 16 and HPV31 (AAVLP-HPV) or placebo. AAVLP-HPV vaccination was well tolerated and induced a modest L2-specific serum antibody titer...

Jade Alvarez, Pola Olczak, Hua-Ling Tsai et al. · 0 citations
#gene editing Open access Sep 2026

59 GPNMB:CD44 Signaling Drives Tumor Progression in Translocation Renal Cell Carcinoma

Abstract Background MiT/TFE-rearranged, translocation renal cell carcinoma (tRCC) is characterized by gene fusions involving TFE3 or TFEB, and is a rare, aggressive non-ccRCC, often occurring in children and with few biomarkers or targeted therapy options. TFE3 is the most commonly translocated gene with ASPSCR1, PRCC...

K. Asrani, Juhyung Woo, Thiago Vidotto et al. · 0 citations

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