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Vanessa K. Morris

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#protein folding Open access Sep 2026

Hierarchical cysteine oxidation controls reversible amyloid formation in an ankyrin repeat protein

It is shown that a zebrafish protein, drP18, can transition into an amyloid fold, driven by a sophisticated two-cysteine oxidation mechanism, suggesting that oxidation-driven amyloid formation can act as a more general mechanism of protein regulation.

A. Sethi, Hannah Darroch, N. J. Magon et al. · 0 citations
Open access Jul 2026

The impact of physiological oxidants on triggering amyloid formation of the cell cycle regulator protein p16INK4A

It is demonstrated that physiological oxidants differ in their ability to induce amyloid transitions in p16, with potential implications for oxidative stress‐mediated inactivation of this cell‐cycle regulator protein.

Briana R. Smith, N. J. Magon, A. Sethi et al. · 0 citations

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