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Author

Verity Ghansah

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Review Open access Sep 2026

Extrachromosomal DNA in Adaptive Tumour Evolution: Mechanisms Driving Plasticity, Drug Resistance and Precision Oncology

Extrachromosomal DNA (ecDNA) has been identified as a critical component of tumour evolution, offering a dynamic genetic and regulatory landscape through which cancer cells can alter oncogene dosage, transcriptional states, and cellular phenotypes. Lacking centromeric and telomeric sequences, ecDNA is inherited in a no...

Verity Ghansah, Yemisi Omotoyosi Adetayo, Oluwabukunmi M. Oluwaniran et al. · 0 citations
Review Open access Jul 2026

CRISPR-Cas9 in Human Health: A Scoping Review of Therapeutic Applications, Safety Challenges, and Ethical Frameworks

CRISPR-Cas9 has demonstrated considerable clinical potential across a range of therapeutic applications, particularly for selected monogenic disorders in which the strongest clinical evidence is currently available.

M. D. Badru, Verity Ghansah, Ifeoluwa Oyinkansola Adesanya et al. · 0 citations
#gene editing Review Open access Aug 2026

Exploring the Potential of CRISPR-Cas9 Gene Editing for Sickle Cell Disease and Malaria Resistance: A Systematic Review

Current evidence supports separate translational pathways in SCD and malaria applications remaining predominantly preclinical, with clinical progress established in SCD and malaria applications remaining predominantly preclinical.

Comfort Ohunene Matthew, B. Inyang, Verity Ghansah et al. · 0 citations

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