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Veronica Kuo

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Open access Sep 2026

Evaluating pharmacological targeting of actin regulatory pathways during aging in C. elegans

Actin is a highly conserved cytoskeletal protein that regulates numerous cellular processes essential for tissue homeostasis and healthy aging. Although genetic studies have established important roles for actin and actin-binding proteins in longevity, pharmacological approaches offer complementary advantages for manip...

Tiffany Wang, Athena Alcala, Daniella Berdan et al. · 0 citations
Open access Aug 2026

Neuronal expression of bromodomain proteins alters neuronal health and peripheral protein homeostasis to promote longevity

It is shown that the neuronal expression of the chromatin reader BET-1 promotes longevity and resilience in C. elegans through signaling mechanisms involving master transcription factors HSF-1 and DAF-16 and neurotransmitter UNC-13.

Naibedya Dutta, Daniel Hicks, Edgar Esparza et al. · 0 citations

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