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Review Open access Oct 2026

Revisiting tuberculosis through the Mtb and host cell extracellular vesicles

Tuberculosis (TB) is one of the deadliest infectious diseases worldwide, with complex and incompletely elucidated pathological mechanisms underlying its recalcitrance to cure. In recent years, the pivotal role of extracellular vesicles (EVs) in host-pathogen interactions has garnered increasing attention. This review s...

Wei Wang, Yi-Jia Liang, Qiu-Xia Gao et al. · 0 citations
#protein folding Open access Nov 2026

Biomimetic mycobacterial dual spatiotemporal targeting induces trained immunity for tuberculosis photothermal immunotherapy and relapse prevention.

These findings show that TDN + AIE@MM integrates physical sterilisation, immunosuppression reversal, and durable immune memory via dual spatiotemporal targeting, effectively addressing the three core challenges in TB therapy, namely delivery barriers, immune evasion, and relapse risk, and offering a promising strategy...

Wei Wang, Xiao-Xue Li, Mei-Jia Pan et al. · 0 citations

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