A universal twist-slide coupling mechanism governs deformations of DNA, RNA, and RNA-DNA hybrid duplexes
Nucleic acid duplexes, including DNA, RNA, and RNA–DNA hybrid (RDH), undergo structural deformations that are essential for genome replication, transcription, and RNA-mediated regulation. However, quantitative measurements and mechanistic understanding of these deformations remain limited. Here, we probe nucleic acid d...
Fujia Tian, Wei Wei, Chen Zhang et al.
· Nature Communications · 0 citations