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Author

Wei Zhang

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Aug 2026

Targeting the METTL14/Wnt9a/β-catenin pathway with pharmacological inhibitors enhances radiotherapy and immunotherapy efficacy in non-small cell lung cancer.

These findings establish METTL14 as a central pharmacological target whose inhibition suppresses the Wnt9a/β-catenin pathway, enhances radiotherapy and anti-PD-1 efficacy, and reduces CSC-driven progression in NSCLC.

Kai-Feng Ji, Rong Yu, Wei Zhang et al. · 0 citations
Aug 2026

Recurrent PIK3CA-E545K mutation promotes cervical cancer growth and invasion via AKT/mTOR signaling

Results provide experimental support for targeting the PI3K/AKT/mTOR axis as a potential therapeutic strategy in cervical cancer through functional and mechanistic link between recurrent PIK3CA-E545K-MUT and aggressive tumor behavior in cervical cancer via AKT/mTOR pathway activation.

Congxiu Huang, Wei Zhang, Xiaoyu Ma et al. · 0 citations

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