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Review Oct 2026

Spatial Plasticity and Multidirectional Crosstalk of Cancer-Associated Adipocytes in Therapy-Remodeled Niches.

Cancer-associated adipocytes (CAAs) are increasingly recognized as active and heterogeneous components of the tumor microenvironment. Initially defined as tumor-adjacent adipocytes characterized by lipid depletion, reduced expression of mature adipocyte markers, and inflammatory activation, CAAs are now understood to e...

Jin-Dong Xie, Ting-Ting Cai, Neng Wang et al. · 0 citations
Jul 2026

METTL5-mediated rRNA modification controls prostate cancer progression through the IRF7/DNA2 axis and mitophagy regulation

The findings uncover an unappreciated mechanism linking rRNA modification to mitochondrial homeostasis through selective translational control, providing new insights into metabolic regulation and revealing actionable vulnerabilities in advanced prostate cancer.

Rui-Feng Yang, Qin-Tao Ge, Feng-Yao Wu et al. · 0 citations

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