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Introduction Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, and ferroptosis-an iron-dependent form of regulated cell death-has been increasingly implicated in AD-related neuronal loss. However, the causal relationship between specific ferroptosis-related genes and AD, particularly within defined...
Seipin is identified as a novel regulator of ferroptosis in the pathogenesis of AD and the potential of the BSCL2-glycine-ferroptosis axis as a therapeutic target is underscored.
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