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Wen-Hui Wu

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Sep 2026

Age-associated chromatin repression of Hippo-Yap signaling drives oogonial stem cell decline in chicken

It is shown that OSC number and proliferative capacity decline significantly from pre-laying to late-laying stages, accompanied by increased follicular atresia, and epigenetic repression of the Hippo–YAP axis suppresses OSC proliferation through epigenetic repression of the Hippo–YAP axis.

Jia-Hui Wei, Jin Wang, Hong-Cai Sun et al. · 0 citations

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