Author

Wen-Zhi He

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Open access Aug 2026

Mitoxyperilysis Drives Immunosuppressive Tumor Microenvironment Remodeling and Hepatocellular Carcinoma Progression via ANXA1-Mediated Macrophage M2 Polarization

The connection between mitoxyperilysis, Annexin A1, and macrophages may help explain immune escape in liver cancer and may guide future biomarker and treatment research.

Meng Qin, Wen-Zhi He, Gang Wu · Cancers · 0 citations

Open access Jul 2026

PDIA6 exacerbates hepatocellular carcinoma via enhancing proteasome-dependent degradation of AKAP12.

This study experimentally validated that PDIA6 promotes the proliferation and metastasis of HCC cells and uncovered the HCC-promoting mechanism of the PDIA6-AKAP12-Wnt signaling axis and highlights its great potential for the development of therapeutic targets in HCC.

Rucheng Yao, Yuhan Yin, Xiaosong Li et al. · Cellular Oncology · 0 citations