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Wendy W. Y. Choi

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#gene editing Open access Sep 2026

HOPX regulates the development and lineage progression of human stem cell-derived outer radial glia-like cells.

Using CRISPR-Cas9 gene editing in human pluripotent stem cells, HOPX is identified as an important regulator of oRG-like cell maintenance and the neurogenic-gliogenic balance, providing insight into the molecular programs governing human neural progenitor expansion.

Xiao-Xue Dong, Wendy W. Y. Choi, Mai Ahmed et al. · 0 citations

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