Weng-Weng Liang

Rosmarinic acid alleviates colitis and repairs mucus barrier damage in a gut microbiota-dependent manner.

Rosmarinic acid (RA) significantly alleviates DSS-induced colitis by repairing the damaged colonic mucus barrier and reversing gut microbiota dysbiosis. However, it remains unclear whether the gut microbiota is required for this protective effect. To address this, pseudo-germ-free mouse models and fecal microbiota tran...