Author

Wentao Shen

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Jul 2026

Precursor supply and translational machinery engineering of Saccharomyces cerevisiae for improving cellular protein content and biomass-based microbial protein bioproduction.

A multilevel engineering strategy to enhance yeast protein production by optimizing precursor supply, translation machinery, and diploid construction provides both improved protein content and key targets for breeding high-protein microbial strains.

Yang Liu, Cai-Ying Jin, Wentao Shen et al. · Bioresource Technology · 1 citation

#protein folding Open access Aug 2026

Ribosome engineering enhances genetic code expansion in Saccharomyces cerevisiae

Genetic code expansion enables the site-specific installation of noncanonical amino acids (ncAAs) into proteins, but its limited efficiency in eukaryotes remains a major barrier to broader application. Here we establish a visual, plug-and-play screening platform to evolve 18S ribosomal DNA in Saccharomyces cerevisiae a...

Xiao-Xu Chen, Wentao Shen, Xian-Qing Chen et al. · Synthetic and Systems Biotec... · 0 citations