Aims: Metabolic syndrome (MetS) is a growing public health burden driven by chronic low-grade inflammation and lipid metabolic dysregulation, with diet as a major modifiable determinant. Proinflammatory diets [assessed by the dietary inflammatory index (DII)] are linked to MetS risk, but the underlying metabolic pathwa...
Jiajun Sang, Ke-Xin Zhang, Cheng-Xia Kan et al.· Metabolic Syndrome and Relat...· 0 citations
A deeper mechanistic understanding of HOX-driven networks will aid the development of innovative biomarkers and therapies, thereby advancing precision medicine in endocrine oncology, and advancing precision medicine in endocrine oncology.
Si-Lin Kong, Ke-Xin Zhang, Cheng-Xia Kan et al.· Medical Oncology· 0 citations
A “metabolic crisis-cascade” framework is proposed, in which progressive disruption of energy metabolism, redox balance, and metal homeostasis acts as a unifying upstream mechanism linking multiple PCD pathways during kidney injury and preventing AKI-to-CKD transition.
Jiajun Sang, Zhen-Tao Guo, Cheng-Xia Kan et al.· Apoptosis· 0 citations
Background Increasing evidence has linked inflammation to Hashimoto’s thyroiditis (HT) etiology. However, the causal role of circulating inflammatory proteins in HT remains uncertain. To investigate this, we conducted a bidirectional Mendelian randomization (MR) study. Methods Genetic data for 91 inflammatory proteins...
Shu-Ting Ding, Wei-Qiang Su, Ming-Hao Wu et al.· Mediators of Inflammation· 0 citations
BACKGROUND
Ischemic heart disease (IHD) remains the leading cause of mortality and disability in the G20, yet member states exhibit heterogeneous epidemiological transitions. Comparative assessments with long-term projections are essential to inform cardiovascular strategies.
AIMS
To comprehensively evaluate the temp...
Yanjia Shi, Kexin Zhang, Sijing Tang et al.· Catheterization and cardiova...· 0 citations
The global burden of NMSC is rising, and men consistently experience higher incidence, mortality, and DALY rates than women, and the expanding sex gap highlights the urgent need for targeted and sex-specific prevention, early detection, and public health interventions.
Wenqiang Zhang, Ke-Xin Zhang, Cheng-Xia Kan et al.· Advances in Skin & Wound Car...· 0 citations
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