This study aims to systematically identify key hub genes in psoriasis pathogenesis through the integration of bioinformatics, machine learning and experimental validation methods, and emerged HPSE emerged as a multifunctional core gene associated with immune dysregulation.
Ya-Qi Zhao, Xiao Liang, Ming-Wei Tang et al.· Frontiers in Immunology· 0 citations
While the systemic lupus erythematosus (SLE), a severe autoimmune disease, is known to relapse frequently after treatment, none of the previous single-cell studies have examined the immune dynamics and their potential contribution to this relapse in the real clinical setting. To address this issue, here we employed sin...
Chen-Rui Xia, J. Qian, Yang Ding et al.· Genomics, Proteomics & Bioin...· 0 citations
The XGBoost machine learning model effectively handles non-linear variables and highlights the core diagnostic importance of patient-reported outcomes (ESSPRI) and traditional clinical features, providing a favorable evaluation tool.
Ya-Qi Zhao, Xunjun Dong, Ping-Ting Yang et al.· Clinical Rheumatology· 0 citations
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