Comparative Value of Traditional versus Novel Immune-Inflammatory Indices in Assessing Disease Activity of Sjögren’s Disease: A Multicenter Cohort Study
The XGBoost machine learning model effectively handles non-linear variables and highlights the core diagnostic importance of patient-reported outcomes (ESSPRI) and traditional clinical features, providing a favorable evaluation tool.
Introduction: Differentiating major organ involvement (MOI) from isolated mucocutaneous manifestations in Behçet’s disease (BD) remains a substantial clinical challenge, particularly in stable outpatients outside acute flares. This study aimed to evaluate the cross-sectional discriminatory utility of complete blood cou...
Süleyman Gül, M. Özdemir, H. Ecesoy· Journal of Clinical Medicine· 0 citations
Objective: The aggregate index of systemic inflammation (AISI) is a recently introduced composite inflammatory marker derived from neutrophil, monocyte, lymphocyte, and platelet counts. This study aimed to evaluate AISI values in patients with Behçet’s disease (BD), compare them with healthy controls, and investigate t...
Zeynep Kaya, S. Ösken· Rheumatology Quarterly· 0 citations
Background: Celiac disease is an enteropathy characterized by intestinal inflammation and systemic immune activation. In recent years, there has been a rising focus on systemic inflammation markers obtained from complete blood count parameters, including the Systemic Immune-Inflammation Index (SII) and the Systemic Inf...
Neslihan Gürcan Kaya, Semih Sandal· Dicle Tıp Dergisi· 0 citations
Background: Identifying novel, reliable blood-based biomarkers is essential to better assess disease activity in idiopathic inflammatory myopathies (IIMs). We aimed to determine serum fatty acid binding protein 3 (FABP3) levels in IIM patients and evaluated their correlations with disease activity, muscle strength, and...
Dorottya Szinay, Katalin Szabó, T. Béldi et al.· Biomolecules· 0 citations
Rheumatoid arthritis (RA) is a chronic inflammatory disease in which accurate assessment of disease activity is essential for optimizing treatment strategies. Hematological indices derived from routine blood tests, such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic im...
Yelitza Velarde-Mejía, Guillermo Velarde Paredes, Ventura Mejia Mena et al.· Clinical Medicine Insights:...· 0 citations
Neutrophil-to-lymphocyte ratio and systemic immune-inflammation index improved cardiovascular risk prediction for patients with psoriasis with atherosclerosis, enabling effective risk stratification.
Miao Zhang, Mun-Gwan Hong, Rui-Qing Cao et al.· JID Innovations· 0 citations
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