Author

Xiaohui Liao

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#gene editing Review Open access Sep 2026

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

ABSTRACT Mitochondria, as organelles with a critical role in maintaining cellular activities, are also vulnerable to dysfunction, which contributes substantially to the pathogenesis of various systemic diseases. Nanomaterials, owing to their tunable physicochemical properties and precise bio‐interfacial capabilities, o...

Yuan-Yuan Su, Zhi-Yan Gong, Jiao Mu et al. · Advancement of science · 0 citations

Open access Jul 2026

LncPTEC mediated homocysteine accumulation elevates oxidative stress via UBQLN1-dependent MTHFD1 ubiquitination in DKD.

It is shown that homocysteine accumulation in proximal tubular epithelial cells (PTECs) is a significant contributor to mitochondrial oxidative stress in DKD and the role of the lncPTEC/MTHFD1 axis in Hcy-mediated mitochondrial oxidative stress is elucidated, offering potential diagnostic biomarkers and therapeutic tar...

Qi-Jia Wang, Tian-Hui Wu, Peilin Li et al. · Cell Death and Disease · 0 citations