High TNFAIP3 expression and its induced M2-like macrophage polarization serve as prognostic markers for postsurgical distant metastasis in breast cancer
Postsurgical distant metastasis remains the leading cause of breast cancer-related mortality, yet reliable biomarkers for identifying patients at high risk of recurrence are lacking. Tumor necrosis factor alpha-induced protein 3 (TNFAIP3) and tumor-associated macrophages (TAMs) contribute to an immunosuppressive...