Author

Xin Liu

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Open access Sep 2026

A Lynch Syndrome Family With Germline MLH1 c.931A>G Showing Preserved Tumor MMR Immunostaining but MSI‐H Status: A Case Report

ABSTRACT Lynch syndrome screening may be complicated by discordant tumor testing results. We report a family carrying the germline MLH1 c.931A>G (p.Lys311Glu) variant in which both the proband and his father had colorectal tumors with retained mismatch repair protein expression by immunohistochemistry but microsatellit...

Jing-Jing Cai, Zhuo-Ying Li, Ting-Ting Han et al. · Clinical Case Reports · 0 citations

Aug 2026

Integrated bulk, single-cell and spatial transcriptomic analyses identify KIFC1 as a driver of malignant progression in lung adenocarcinoma

Computational analyses suggest a potential relationship between KIFC1-associated malignant states and tumor microenvironmental signaling, supporting its value as a prognostic biomarker and potential therapeutic target.

Linghan Tian, Yuan-Biao Wang, Li Huang et al. · Molecular Biology Reports · 0 citations