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Xin-Miao He

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Open access Oct 2026

Pyrimidine Metabolic Dysregulation Following pyrR Knockout Attenuates the Anti-Biofilm, Anti-Inflammatory, and Antioxidant Activities of Lacticaseibacillus casei Cell-Free Supernatant

Pathogenic infections caused by intestinal microecological imbalance pose a critical threat to livestock breeding and human health. Multiple probiotic functions of Lacticaseibacillus casei (L. casei), an important probiotic, are modulated by pyrR-mediated pyrimidine metabolism. This study used L. casei isolated from th...

Yao Jiang, Feng-Ze Han, Xin-Miao He et al. · Biology · 0 citations

Open access Oct 2026

Cold Stress-Induced Adipose Tissue Remodeling in Min pigs: Involvement of the ADRB3-ERK Axis, Autophagy, and Inflammatory Pathways

Cold stress induces adaptive remodeling of adipose tissue, yet the coordinated molecular network, particularly the interplay between upstream signaling pathways and downstream cellular responses, remains incompletely understood. This study investigated whether cold stress regulates adipose tissue beiging, apoptosis, an...

Shuo Yang, He-Shu Chen, Dong-Jie Zhang et al. · Biomolecules · 0 citations

#gene editing Open access Sep 2026

Meta-Analysis of Porcine Beige Adipogenesis with Cross-Species CD137-CD137L Molecular Docking: Potential Implications for Pig-to-Human Xenotransplantation

The findings support a hypothesis that porcine adipocyte beiging and CD137-related cross-species interactions may be relevant to xenograft immunometabolism; direct experimental validation in xenotransplantation models is required.

Zhen-Hua Guo, Liang Wang, Xin-Miao He et al. · Cells · 0 citations