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Author

Xiuli Lian

2 papers indexed here

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Aug 2026

YAP/TEAD complex restricts H3K27ac deposition to suppress testosterone synthesis in adult Leydig cells

It is demonstrated that YAP/TEAD orchestrates postnatal Leydig cell maturation by epigenetically repressing the steroidogenic program, revealing a novel role for the Hippo pathway in male reproductive development and providing insights into the pathogenesis of iNOA.

Ze-Yu Lin, Shanshan Luo, Mei Zheng et al. · 0 citations
Aug 2026

Perfluorodecanoic Acid (PFDA) induces ovarian toxicity and premature aging via mitochondrial dysfunction.

Perfluorodecanoic acid (PFDA) is a perfluoroalkyl substance characterized by high environmental persistence and bioaccumulation potential, with a propensity to accumulate in the reproductive system. However, its toxicological effects on ovarian function remain poorly understood. This study employed mouse primary ovaria...

Yang Su, Huiyi Xie, Xiuli Lian et al. · 0 citations

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