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Author

Xuefang Ma

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3 papers indexed here

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Review Sep 2026

Neuro‐Immune Interaction: A New Therapeutic Target for Cardiovascular Diseases

Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide, underscoring the need for integrative pathophysiological frameworks beyond cardiomyocyte‐centered models. This review summarizes recent advances in cardiac neuroimmunology and examines how interactions among the nervous, immune...

Xue-Fang Ma, Ke Yang, Ao-Di Fan et al. · 0 citations
Review Open access Aug 2026

The Heart–Kidney Axis in Heart Failure and Chronic Kidney Disease: Mechanisms, Mediators, and Therapeutic Implications

The heart–kidney axis has emerged as a central framework for understanding the bidirectional interactions that drive cardiorenal syndrome and broader cardiovascular–kidney–metabolic (CKM) disease. However, existing interpretations have often emphasized hemodynamic and neurohormonal mechanisms without fully integrating...

Ao-Di Fan, Xin-Wei Chen, Ke Yang et al. · 0 citations
Review Open access Aug 2026

TREM2 signaling in cardiovascular disease: macrophage heterogeneity, timing, and therapeutic opportunity.

This review systematically delineates the spatiotemporal dynamics and functional duality of TREM2+ macrophages across major cardiovascular conditions, and further evaluates the current evidence and limitations of soluble TREM2 (sTREM2) as a candidate biomarker and critically appraises translational strategies targeting...

Ke Yang, Xue-Fang Ma, Bin-Yan Wang et al. · 1 citation

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