Oct 2026
Structural basis and rational engineering of a thermophilic Cas13a for robust RNA detection.
S. J. Oladeji, Diego H. Gonzalez, Xiang-Yu Deng et al.
· Cell Chemical Biology · 0 citations
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2026
Constructing Drive-and-Process (DAP) CRISPR Guide RNA Arrays for Multiplexed Base- and Prime-Editing.
Devin A. Golla, Tyler C. Daniel, Logan Haugh et al.
· Methods in molecular biology · 0 citations
Adaptive model-guided protein evolution with sparse data optimizes compact eukaryotic genome editors.
EvoMax is established as an integrated strategy for engineering compact eukaryotic Fz2 genome editors and FanzMAX v3-hLa is identified as a high-efficiency programmable nuclease for mammalian genome editing.
Shijie Wan, J. Gold, Pranay Vure et al.
· Nature Biotechnology · 1 citation