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Xue-Lian Sun

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#protein folding Open access Sep 2026

CCNB1IP1 regulatory evolution underlies gradual increases in cortical size and folding in primates.

The gradual expansion and folding of the cortex are key factors in human cognitive evolution, yet their molecular underpinnings remain not well understood. Here we identify cyclin B1 interacting protein 1 (CCNB1IP1) gene as a key regulator of human brain evolution using tree shrew as an outgroup. In primates, CCNB1IP1...

Ting Hu, Peng-Cheng Ma, Yi-Fan Kong et al. · 0 citations
Review Jul 2026

Adult neural stem cell pools in homeostasis and pathogenesis.

Adult neural stem cells (NSCs) persist throughout life in discrete neurogenic niches of the mammalian brain, most prominently the subventricular zone (SVZ), the subgranular zone (SGZ) of the hippocampal dentate gyrus, and the hypothalamic ventricular zone (HVZ). These niches harbor regionally specialized NSC population...

Si Li, Xiang Shi, Xue-Lian Sun et al. · 0 citations

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