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Xuemei Li

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Open access Oct 2026

A Sequentially Activated Nanoreactor With DNAzyme Cascade for Precise Breast Cancer Theranostics.

Current oncological interventions are often limited by insufficient tumor selectivity and off-target toxicities, necessitating intelligent therapeutic platforms with precision-gated activation. In this study, a sequentially activated nanoreactor (GOx-MnCaP-DD) is designed for integrated breast cancer theranostics, comb...

Geng Yang, Wei-Fang Gong, You-Cheng Yang et al. · 0 citations
Aug 2026

A flexible hydrogel-based SERS sensor for multi-target detection of microbial metabolites in deep-sea environments.

As research on microorganisms in extreme deep-sea environments advances, there is an urgent need for in-situ, highly sensitive detection technologies for their metabolites. However, the extreme conditions of the deep sea pose significant challenges to sensor pressure resistance, anti-interference capability, and operat...

Tingting Zhao, Si-Yu Wang, Xin Zhang et al. · 0 citations
#gene editing Aug 2026

The spatiotemporal-specific regulation of cell wall-related proteins promotes the secretion of pigments in Antarctic fungi Geomyces sp. wnf-18c.

The exogenous addition of xylose as a signal to initiate genetic editing achieved the spatiotemporal regulation of the target gene-activating gene editing that restricts growth only after the completion of the strain's growth phase, and raised the total pigment yield.

Jiawen Du, Long-Xiang Liu, Jia-Wen Gao et al. · 0 citations

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