Author

Xun Zhang

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Open access Sep 2026

Connectome gradient dysfunction in earthquake-induced posttraumatic stress disorder and its association with gene expression and neurotransmitter profiles

Abstract Background Posttraumatic stress disorder (PTSD) exhibits disrupted functional organization of brain networks involving sensory and association cortices. Connectome studies reveal a principal unimodal-to-transmodal gradient in the brain functional network that supports the spectrum from sensation to cognition....

Xun Zhang, Wen-Xiong Liu, Li Chen et al. · Psychological Medicine · 0 citations

Jul 2026

Trait emotional regulation mediates the protective role of resting-state brain activity against depressive symptoms in late adolescence.

BACKGROUND Depression is a common psychiatric condition posing serious threats to individual physical and mental health. While previous studies have demonstrated that trait emotional regulation (TER) is a protective factor for depression, the neural correlates between TER and depression remain unclear, especially in ad...

Xun Zhang, Min He, Yi-Ling Guo et al. · Journal of Affective Disorde... · 0 citations

#edge computing Aug 2026

Edge-centric brain connectomes reveal two molecularly distinct neurobiological subtypes of adolescent major depressive disorder.

This study investigated the neural and molecular bases of individual differences in adolescent MDD patients by integrating a novel edge-centric brain connectome with transcriptomic and neurotransmitter profiles, and identified two robust adolescent MDD subtypes.

Yingbo Shao, Bao-Lin Wu, Xun Zhang et al. · European Child and Adolescen... · 0 citations