[IGFBP-4 improves synovitis by reducing M1 polarization of macrophages via the Wnt/β-catenin pathway].
Investigating the mechanism by which insulin-like growth factor binding protein 4 (IGFBP-4) ameliorates synovial inflammation in osteoarthritis by inhibiting M1-type polarization of synovial macrophages via the Wnt/β-catenin signaling pathway demonstrated that the co-localization of F4/80 and iNOS in the synovium was s...