Engineering a stable high-copy episomal plasmid in Yarrowia lipolytica.
Episomal plasmids are widely used in yeast metabolic engineering for their flexibility and high transformation efficiency. However, their application in Yarrowia lipolytica is often limited by low copy number and insufficient genetic stability. In this study, a robust episomal plasmid that balanced genetic stability an...
Feng-Yi Li, Si-Rui Peng, Huang-Wei Xu et al.
· FEMS Yeast Research · 0 citations