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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Yamin Zhufu

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Aug 2026

Enantiodivergent C3-Selective Reduction of Arylvinyl-Substituted 3,5-Dicarbonyl Esters Enabled by Engineered Ketoreductases.

Chiral arylvinyl-substituted 3-hydroxy-5-oxo esters are valuable motifs in pharmaceuticals, yet their enantiocontrolled synthesis remains challenging. Herein, we report a biocatalytic system using ketoreductases (KREDs) for the highly C3-selective reduction of arylvinyl-substituted 3,5-dicarbonyl esters. Through semira...

Xiao-Qiu Wu, Ming-Yu Zhang, Ming-Yang Yao et al. · 0 citations

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