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Sep 2026

Adjunctive Akkermansia muciniphila postbiotic supplementation modulates metabolic and endocrine profiles in obesity-associated polyendocrine metabolic ovarian syndrome: A randomized controlled trial.

BACKGROUND & AIMS As a flagship next-generation probiotic, Akkermansia muciniphila (AKK) has been extensively validated for its prominent therapeutic advantages against metabolic diseases. However, clinical research on AKK remains scarce owing to its exclusion from the Official Catalog of Approved Food Microbial Strain...

Qing-Wei Zeng, Yan Liu, Yao Kong et al. · 0 citations
Aug 2026

Quercetin Ameliorates Imatinib-Induced Ovarian Damage by Regulating Mitochondrial Dysfunction and PANoptosis via the RAF1-ERK1/2-Drp1 Axis.

In vitro experiments revealed that IMA induced PANoptosis, characterized by membrane blebbing and swelling, pyknosis, as well as rupture of the nuclear and plasma membranes observed, which suppressed IMA-induced PANoptosis, and improved granulosa cell viability and oocyte quality.

Qing-Hui Li, Min Ji, Yan Zhou et al. · 0 citations

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