Author

Yao-Yao Zhou

2 papers indexed here

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Open access Sep 2026

HIF1A+CSF3R+ neutrophils-dominated hypoxic niche induced metabolic reprogramming for neoadjuvant therapy resistance in NSCLC

Abstract Background Non-small cell lung cancer (NSCLC) is one of the frequently occurring cancers characterized by molecular heterogeneity and multiple immune cell infiltration patterns, which are associated with treatment sensitivity and resistance. However, the specific microenvironmental cells and their mechanisms t...

Yao-Yao Zhou, Zi-Yun Liu, Parhat Kaysar et al. · Journal for ImmunoTherapy of... · 0 citations

Open access Sep 2026

Single-cell landscape reveals PLPP2 upregulation underlying radiotherapy resistance and immune microenvironment remodeling in pancreatic cancer

Highlights • Single-cell transcriptomic profiling of multicenter pancreatic cancer radiotherapy cohorts identified PLPP2 as a key driver of radiotherapy resistance and immune microenvironment remodeling.• Random forest model identified PLPP2 as an important marker for promoting malignant progression, immune dysregulati...

Yi-Fei Wang, Parhat Kaysar, Yi-Jian Ma et al. · Translational Oncology · 0 citations