Self-Assembled PEDV Virus-Like Particle Nanovaccines Elicit Potent Neutralizing Antibodies and Confer Full Protection in Piglets.
Porcine epidemic diarrhea virus (PEDV) remains a major threat to the global swine industry, with current inactivated vaccines offering limited cross-protection due to imperfect antigen design and weak immune activation. Here, we engineered a full-structural-protein virus-like particle (VLP) co-assembled with PEDV S, M,...