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Caenorhabditis elegans as a Model Host for Fusobacterium nucleatum.
Caenorhabditis elegans is presented as a versatile and tractable model for investigating F. nucleatum virulence determinants and offer a valuable platform for advancing the understanding of its pathogenic potential.
A 3D Tumor Spheroid Platform to Model Fusobacterium nucleatum-Induced Tumorigenesis.
A detailed protocol is presented in which colorectal cancer cells are seeded into ultralow attachment plates and co-cultured with F. nucleatum either prior to spheroid formation, to model early tumor development, or after spheroids have been established, to model tumor progression.